Not in 2.0, but in 2.1 you’ll be able to style one installation based on the hostname being requested. So 2.1 will respond to multiple hostnames and style itself differently for each hostname based on configuration.
I have installed OOD 3.0 and set up hostname profile selection.
In order to get the same OOD portal running under two names, my plan is to copy the apache config and find/replace the ServerName as well as the certificate/private key locations. But I get the feeling that there is a better way. Ideally this could be done in my ood_portal.yml. Is that possible?